Integraslice is designed to provide you with the highest quality slices in the most difficult tissue slicing applications. This is achieved with the following combination of features:

• Precision mechanical movement

• Electronic control system

• Precision blade technology

• Temperature control

• 10 micron per second speed resolution for blade advance and reversing during sectioning.

• Constant feedback system allows cutting speed to be maintained through variations in tissue density.

• Blade returns for next slice at high speed to minimize total sectioning time.

The result is a minimum of induced trauma, and maximum preservation of cell structure and biochemical action.

• A precision mechanical system raises tissue against gravity between slices for maximum accuracy.

• Increments of 1 micron height resolution by stepper motor control.

• Viewing mirror at rear of tissue enables you to see the point of entry.

• Coarse vertical height adjustment of 1mm per second is also available.

Tissue is automatically withdrawn during the reverse stroke so the blade is not drawn across the next slice.

• Liquid Crystal Display (LCD) with associated membrane keypad.
• Easy-to-follow menu available in multiple languages.
• Twin rotary dial knobs offer variable control of the blade advance and return during sectioning and variable control of brightness for the cold light source.
• Two-stage foot-switch; first starts the blade oscillating and the second starts the advance of the blade.
• Thus, when the footswitch is released the tissue is never pushed against a static blade.
• The enclosure gives style and cleanliness, sealing against accidental spillage and is tolerant of salt and sugar a.c.s.f. Easy access to change the light source bulb and the drive belts.

Model 7550PSDS

Programmable cutting profiles of Speed, Distance and Section thickness

PSDS denotes Programmable cutting profiles of Speed, Distance and Section thickness. Using the rotary dial knob, the speed of advance can be slowed through one area and increased through another, with a resolution of 10 microns per second. By selecting record mode and going manually through the first slice, the instrument effectively learns the changes of speed and distance as the blade travels. When the third parameter of section thickness is entered and the number of slices required is set, the instrument will then faithfully reproduce the parameters that it recorded. This frees the operator’s hands enabling them to harvest the slices in the shortest possible time.

Model 7550PSDS Shown with optional accessories:

Model 7550LS Cold Light Source

Model 7550IM Inspection Microscope

• Campden's Precision Blades in Zirconium Ceramic and Stainless Steel
• Temperature Controlled Peltier Tissue Baths
• Cold Light Source
• Magnifying Glass or Inspection Microscope
• Autoclavable Baths
• Autoclavable Cutting Head
• Tilting Tissue Mount

Model 7550MM

Motorized or Manual advance of the oscillating blade

Features include a set speed motorized advance/manual advance controlled by a rotary dial knob.

Amplitude of oscillation can be manually adjusted.

MM denotes Manual or Motorized blade advance. This model has all the fine control of the PSDS but without the programmability or the DASA control. The amplitude is manually adjustable between 0.5mm to 1.5mm at a maximum oscillation speed of 80Hz. The manual advance offers the fingertip sensitivity of the rotary dial knob. The set speed advance gives repeatability and consistency. Visually the MM and the PSDS models are similar with the only differences appearing in the menu selections and membrane switch user interface.

Development of our blade technology has been integral to our Microtome design. The blades are available in stainless steel and zirconium ceramic. Due to their special shape, they fit into Campden’s blade holder so that the tissue returns to the perfused a.c.s.f. as quickly as possible. See pages 11 and 12 for further details.